Welcome to InterProSurf
InterProSurf predicts interacting residues on protein surfaces using structural information from PDB complexes or user‑provided models.
PDB Complex Interface Analysis
Identify interface residues in experimentally determined protein complexes.
Go to PDB Complex →
User Complex Interface Analysis
Analyze protein–protein interfaces in your own structural models.
Go to User Complex →
Patch & Cluster Analysis
Predict interacting residues on monomeric protein surfaces.
Patch Analysis →
Cluster Analysis →
InterProSurf Surface Visualization
References
- Negi SS, Schein CH, Oezguen N, Power TD, Braun W. InterProSurf: a web server for predicting interacting sites on protein surfaces. Bioinformatics. 2007;23:3397–3399.
- Negi SS, Braun W. Statistical analysis of physical–chemical properties and prediction of protein–protein interfaces. J Mol Model. 2007;13:1157–1167.
- Negi SS, Kolokoltsov AA, Schein CH, Davey RA, Braun W. Determining functionally important amino acid residues of the E1 protein of Venezuelan equine encephalitis virus. J Mol Model. 2006;12:921–929.
This service is provided freely to the scientific community for research purposes. There is no warranty, expressed or implied. The user assumes all responsibility for the use, misuse, or inability to use this service.