Cross-React Web Server

Cross-React: Prediction of allergen cross-reactivity

Submit IgE binding site residues and a PDB file to search allergenic protein structures in SDAP for potential cross-reactivity. Version 2.0 includes minor bug fixes and supports searching over 1500 allergen structures.

Negi S.S. and Braun W, Cross-React: a new structural bioinformatics method for predicting allergen cross-reactivity.
Bioinformatics 33 (7): 1014–1020, 2017
PDF

For protein complexes, IgE binding residues can be identified using: pdbcomplex or usercomplex.

Submit a Cross-React Query
Provide IgE binding residues and upload a PDB structure.
Version 2.0

Example: 42,43,44,45,46,47,48,49,50,51

Example Analysis

Example Input (Bet v 1):

Example input

Example Outputs:

Output 1 Output 2 Output 3 Output 4